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KMID : 0363819950290030287
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Korean Journal of Nuclear Medicine
1995 Volume.29 No. 3 p.287 ~ p.293
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The Performance of Ictal Brain SPECT for Localizing Epileptogenic foci in Temporal Lobe Epilepsies
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김은실
이동수/정준기/이명철/고창순/장기현/이상건/정천기
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Abstract
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Anterior temporal lobectomy has become a widely used resective surgery in patients with medically intractable temporal lobe epilepsies. Prerequisites of this resection include the accurate localization of the epileptogenic focus and the
determination
that the proposed resection would not result in unacceptable postoperative memory or language deficits. The purpose of this study was to evaluate the performance of ictal SPECT compared to MRI findings for localization of epiletogenic foci in
this
group
of patients. 11 patients who had been anterior temporal lobectomy were evaluated with ictal 99mTc-HMPAO SPECT and MRI. MRI showed 8/11(73%) concordant lesion to the side of surgery and ictal SPECT also showed 8/11(73%) concordant hyperperfusion.
In
3
cases with incorrect or nonlocalizing findings of MRI, ictal SPECT showed concordant hyperperfusion. In 2 cases confirmed by pre-resectional invasive EEG, MRI showed bilateral and contralateral lesion but ictal SPECT showed concordant
hyperperfusion. 3
delayed injection of ictal SPECT showed discordant hyperperfusion. Thus, ictal SPECT was a useful method for localizing epileptogenic foci in temporal lobe epilepsies and appeared complementay to MRI.
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KEYWORD
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